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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS39
All Species:
32.73
Human Site:
S439
Identified Species:
60
UniProt:
Q96JC1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JC1
NP_056104.2
886
101809
S439
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Chimpanzee
Pan troglodytes
XP_510331
886
101752
S439
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Rhesus Macaque
Macaca mulatta
XP_001102792
886
101693
S439
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Dog
Lupus familis
XP_849407
886
101720
S439
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5L3
886
101674
S439
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Rat
Rattus norvegicus
XP_001075756
886
101629
S439
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518189
1309
145152
S862
N
D
S
E
Q
Q
S
S
T
S
P
L
M
E
G
Chicken
Gallus gallus
NP_001026365
875
100503
S428
N
D
S
D
H
Q
S
S
T
S
P
L
M
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
V435
L
I
S
Y
L
H
E
V
R
S
S
D
I
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650702
876
100146
R443
I
E
Y
L
A
W
A
R
Q
R
E
V
V
K
L
Honey Bee
Apis mellifera
XP_392710
866
100055
I434
K
A
K
D
K
D
N
I
K
E
K
S
L
I
E
Nematode Worm
Caenorhab. elegans
NP_001041163
923
104932
S449
E
L
Y
N
R
L
Y
S
S
G
A
A
K
K
T
Sea Urchin
Strong. purpuratus
XP_798217
824
94304
M432
S
Q
Q
V
T
T
A
M
P
S
T
I
C
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
98
N.A.
97.4
96.8
N.A.
59.2
92.7
N.A.
26.4
N.A.
35.4
42.4
31.7
51.5
Protein Similarity:
100
99.8
99.7
99.3
N.A.
98.9
98.5
N.A.
62.8
96.1
N.A.
46.8
N.A.
55.6
62
52.5
68.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
100
N.A.
13.3
N.A.
0
6.6
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
N.A.
20
N.A.
33.3
20
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
16
0
0
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
62
0
62
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
8
0
8
0
0
8
0
0
8
8
0
0
70
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
70
% G
% His:
0
0
0
0
54
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
0
0
8
8
8
0
% I
% Lys:
8
0
8
0
8
0
0
0
8
0
8
0
8
16
0
% K
% Leu:
8
8
0
8
8
8
0
0
0
0
0
62
8
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
62
0
0
% M
% Asn:
62
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
62
0
0
0
0
% P
% Gln:
0
8
8
0
8
62
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
8
8
8
0
0
0
0
0
% R
% Ser:
8
0
70
0
0
0
62
70
8
77
8
8
0
0
0
% S
% Thr:
0
0
0
0
8
8
0
0
62
0
8
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
8
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _